| Children |
| + | 1. William Jesse LOWTHER, b. 1791, d. Bef 1840 (Age 48 years) |
| | 2. Uriah LOWTHER, b. CA 1793, d. IN YOUTH |
| + | 3. Mary Ann LOWTHER, b. 26 Oct 1793, Lewis Co, (W)VA , d. 1 Sep 1876, Roane Co, WV (Age 82 years) |
| + | 4. Margaret LOWTHER, b. 1794, d. West Milford, Harrison Co, WV  |
| + | 5. Sarah "Sally" LOWTHER, b. 10 May 1795, Harrison Co, (W)VA , d. 22 May 1870, Gilmer Co, WV (Age 75 years) |
| + | 6. Jesse LOWTHER, Jr., b. CA 1799, Virginia , d. Bef Jun 1880, Little Rock, Pulaski Co, AR (Age ~ 81 years) |
| + | 7. Elias J. LOWTHER, b. 1 Jan 1801, Wood Co, (W)VA , d. 27 Feb 1877, Palestine, Wirt Co, WV (Age 76 years) |
| + | 8. Robert H. LOWTHER, b. CA 1802, d. CA 1838, Mississippi (Age ~ 36 years) |
| + | 9. Sudna Alcinda LOWTHER, b. 1803, d. 1867, West Milford, Harrison Co, WV (Age 64 years) |
| + | 10. Elizabeth "Betsy" LOWTHER, b. 8 Oct 1810, Harrison Co, (W)VA , d. 10 Apr 1859, Lewis Co, (W)VA (Age 48 years) |
| | 11. Drusilla LOWTHER, b. CA 1814, Virginia  |
| | 12. Millie LOWTHER |
|